Aerobic Bacteriological Study of Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Identifieur interne : 000980 ( Main/Exploration ); précédent : 000979; suivant : 000981Aerobic Bacteriological Study of Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Auteurs : Hariom SharanSource :
- Journal of Clinical and Diagnostic Research : JCDR [ 2249-782X ] ; 2015.
Abstract
The natural history of chronic obstructive pulmonary disease is characterized by frequent exacerbations. Majority of exacerbations are infectious and bacteria responsible for 30-50% of these cases. The purpose of this study was to determine the bacteriology of acute exacerbations of chronic obstructive pulmonary disease in hospitalized patients in our institution and their antibiotic susceptibility pattern to formulate cost effective antibiotic strategy and reducing the emergence of drug resistance.
One hundred and seven clinically diagnosed cases of acute exacerbations of chronic obstructive pulmonary disease admitted in medicine, tuberculosis and chest wards were selected for the study. Direct gram stain was done for all sputum samples. The suitable sputum samples were cultured. Identification of organism and antimicrobial susceptibility testing was done by standard microbiological techniques.
Our study showed growth of pathogenic organisms in 41.12% cases. Males (67.29%) are more affected than females (32.71%). Gram negative bacilli were more isolated than gram positive cocci. The commonest isolate was
In developing country like India acute exacerbations of chronic obstructive pulmonary disease is common in adults more than 50 years of age due to smoking habits and high indoor pollution. This leads to a major impact on the quality of life of patients with the condition. They are a major cause of hospital admission and health care utilization.
Url:
DOI: 10.7860/JCDR/2015/14515.6367
PubMed: 26435942
PubMed Central: 4576533
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000018
- to stream Pmc, to step Curation: 000018
- to stream Pmc, to step Checkpoint: 000373
- to stream Ncbi, to step Merge: 000494
- to stream Ncbi, to step Curation: 000494
- to stream Ncbi, to step Checkpoint: 000494
- to stream Main, to step Merge: 000982
- to stream Main, to step Curation: 000980
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Aerobic Bacteriological Study of Acute Exacerbations of Chronic Obstructive Pulmonary Disease</title>
<author><name sortKey="Sharan, Hariom" sort="Sharan, Hariom" uniqKey="Sharan H" first="Hariom" last="Sharan">Hariom Sharan</name>
<affiliation><nlm:aff id="aff1"> Associate Professor, Department of Microbiology,<institution>Sri Aurobindo Medical College and Post Graduate Institute</institution>
,<addr-line>Indore, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">26435942</idno>
<idno type="pmc">4576533</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576533</idno>
<idno type="RBID">PMC:4576533</idno>
<idno type="doi">10.7860/JCDR/2015/14515.6367</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">000018</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000018</idno>
<idno type="wicri:Area/Pmc/Curation">000018</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000018</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000373</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000373</idno>
<idno type="wicri:Area/Ncbi/Merge">000494</idno>
<idno type="wicri:Area/Ncbi/Curation">000494</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000494</idno>
<idno type="wicri:doubleKey">2249-782X:2015:Sharan H:aerobic:bacteriological:study</idno>
<idno type="wicri:Area/Main/Merge">000982</idno>
<idno type="wicri:Area/Main/Curation">000980</idno>
<idno type="wicri:Area/Main/Exploration">000980</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Aerobic Bacteriological Study of Acute Exacerbations of Chronic Obstructive Pulmonary Disease</title>
<author><name sortKey="Sharan, Hariom" sort="Sharan, Hariom" uniqKey="Sharan H" first="Hariom" last="Sharan">Hariom Sharan</name>
<affiliation><nlm:aff id="aff1"> Associate Professor, Department of Microbiology,<institution>Sri Aurobindo Medical College and Post Graduate Institute</institution>
,<addr-line>Indore, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of Clinical and Diagnostic Research : JCDR</title>
<idno type="ISSN">2249-782X</idno>
<idno type="eISSN">0973-709X</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>The natural history of chronic obstructive pulmonary disease is characterized by frequent exacerbations. Majority of exacerbations are infectious and bacteria responsible for 30-50% of these cases. The purpose of this study was to determine the bacteriology of acute exacerbations of chronic obstructive pulmonary disease in hospitalized patients in our institution and their antibiotic susceptibility pattern to formulate cost effective antibiotic strategy and reducing the emergence of drug resistance.</p>
</sec>
<sec><title>Materials and Methods</title>
<p>One hundred and seven clinically diagnosed cases of acute exacerbations of chronic obstructive pulmonary disease admitted in medicine, tuberculosis and chest wards were selected for the study. Direct gram stain was done for all sputum samples. The suitable sputum samples were cultured. Identification of organism and antimicrobial susceptibility testing was done by standard microbiological techniques.</p>
</sec>
<sec><title>Results</title>
<p>Our study showed growth of pathogenic organisms in 41.12% cases. Males (67.29%) are more affected than females (32.71%). Gram negative bacilli were more isolated than gram positive cocci. The commonest isolate was <italic>Klebsiella pneumoniae</italic>
15 (38.46%), followed by <italic>Staphylococcus</italic>
aureus 9 (23.08%), <italic>Streptococcus</italic>
species 6 (15.39%), <italic>Pseudomonas aeruginosa</italic>
4 (10.26%), <italic>E.coli</italic>
2 (5.13%), <italic>Acinetobacter</italic>
species 2 (5.13%) and <italic>Enterobacter</italic>
species 1(2.56%). The antibiotic susceptibility reveals that vancomycin, linezolid, azithromycin and clarithromycin were most effective drugs for gram positive cocci, meropenem & piperacillin-tazobactam for gram negative bacilli and amikacin & levofloxacin for both gram positive cocci & gram negative bacilli.</p>
</sec>
<sec><title>Conclusion</title>
<p>In developing country like India acute exacerbations of chronic obstructive pulmonary disease is common in adults more than 50 years of age due to smoking habits and high indoor pollution. This leads to a major impact on the quality of life of patients with the condition. They are a major cause of hospital admission and health care utilization.</p>
</sec>
</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Sharan, Hariom" sort="Sharan, Hariom" uniqKey="Sharan H" first="Hariom" last="Sharan">Hariom Sharan</name>
</noCountry>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000980 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000980 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= CovidV1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:4576533 |texte= Aerobic Bacteriological Study of Acute Exacerbations of Chronic Obstructive Pulmonary Disease }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:26435942" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a CovidV1
This area was generated with Dilib version V0.6.33. |